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1

Chemical Synthesis of the Second Messenger Nicotinic Acid Adenine Dinucleotide Phosphate by Total Synthesis of Nicotinamide Adenine Dinucleotide Phosphate

James Dowden, Christelle Moreau, Richard S. Brown, Georgina Berridge, Antony Galione, Barry V. L. Potter

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 186 KB

english, 2004

2

Chemical Synthesis of the Second Messenger Nicotinic Acid Adenine Dinucleotide Phosphate by Total Synthesis of Nicotinamide Adenine Dinucleotide Phosphate

James Dowden, Christelle Moreau, Richard S. Brown, Georgina Berridge, Antony Galione, Barry V. L. Potter

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

3

10.1038/18032

Cancela, Jose Manuel, Churchill, Grant C., Galione, Antony

Journal:

Year:

1999

Language:

english

File:

PDF, 1.32 MB

english, 1999

4

2′-Deoxy Cyclic Adenosine 5′-Diphosphate Ribose Derivatives: Importance of the 2′-Hydroxyl Motif for the Antagonistic Activity of 8-Substituted cADPR Derivatives

Zhang, Bo, Wagner, Gerd K., Weber, Karin, Garnham, Clive, Morgan, Anthony J., Galione, Antony, Guse, Andreas H., Potter, Barry V. L.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.34 MB

english, 2008

5

A two-pore channel protein required for regulating mTORC1 activity on starvation

Chang, Fu-Sheng, Wang, Yuntao, Dmitriev, Phillip, Gross, Julian, Galione, Antony, Pears, Catherine

Journal:

Year:

2020

Language:

english

File:

PDF, 6.27 MB

english, 2020

6

ChemInform Abstract: Development of Inositol-Based Antagonists for the D-myo-Inositol 1,4,5-Triphosphate Receptor.

Neil S. Keddie, Yulin Ye, Tashfeen Aslam, Tomas Luyten, Davide Bello, Clive Garnham, Geert Bultynck, Antony Galione, Stuart J. Conway

Journal:

Year:

2011

File:

PDF, 25 KB

2011

7

Flipping the switch: How a sperm activates the egg at fertilization

John Parrington, Lianne C. Davis, Antony Galione, Gary Wessel

Journal:

Developmental Dynamics

Year:

2007

Language:

english

File:

PDF, 454 KB

english, 2007

8

Aplysia californica mediated cyclisation of novel 3′-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5′-diphosphate ribose

Christopher J.W Mort, Marie E Migaud, Antony Galione, Barry V.L Potter

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 404 KB

english, 2004

9

Refinement of a radioreceptor binding assay for nicotinic acid adenine dinucleotide phosphate

Alexander M. Lewis, Roser Masgrau, Sridhar R. Vasudevan, Michiko Yamasaki, John S. O’Neill, Clive Garnham, Kristin James, Andrew Macdonald, Mathias Ziegler, Antony Galione, Grant C. Churchill

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 492 KB

english, 2007

10

Cell-Permeant Small-Molecule Modulators of NAADP-Mediated Ca2+ Release

James Dowden, Georgina Berridge, Christelle Moreau, Michiko Yamasaki, Grant C. Churchill, Barry V.L. Potter, Antony Galione

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 154 KB

english, 2006

11

7-Deaza cyclic adenosine 5′-diphosphate ribose: first example of a Ca2+-mobilizing partial agonist related to cyclic adenosine 5′-diphosphate ribose

Victoria C. Bailey, Jaswinder K. Sethi, Simon M. Fortt, Antony Galione, Barry V.L. Potter

Journal:

Chemistry & Biology

Year:

1997

Language:

english

File:

PDF, 2.44 MB

english, 1997

12

Cyclic ADP-ribose and the regulation of calcium-induced calcium release in eggs and cardiac myocytes

Antony Galione, Yi Cui, Ruth Empson, Shigao Iino, Heather Wilson, Derek Terrar

Journal:

Cell Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 818 KB

english, 1998

13

The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca2+release channels

Antony Galione, A. Mark Evans, Jianjie Ma, John Parrington, Abdelilah Arredouani, Xiaotong Cheng, Michael X. Zhu

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

14

Physiological roles of NAADP-mediated Ca2+signaling

Antony Galione, John Parrington, Tim Funnell

Journal:

SCIENCE CHINA Life Sciences

Year:

2011

Language:

english

File:

PDF, 760 KB

english, 2011

15

Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP)

Michiko Yamasaki, Grant C. Churchill, Antony Galione

Journal:

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

16

cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis

Galione, Antony, White, Alison, Willmott, Nicholas, Turner, Michelle, Potter, Barry V. L., Watson, Stephen P.

Journal:

Year:

1993

File:

PDF, 488 KB

1993

17

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

Lloyd-Evans, Emyr, Morgan, Anthony J, He, Xingxuan, Smith, David A, Elliot-Smith, Elena, Sillence, Daniel J, Churchill, Grant C, Schuchman, Edward H, Galione, Antony, Platt, Frances M

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 646 KB

english, 2008

18

Ca2+ release induced by cyclic ADP-ribose

Antony Galione, Alison White

Journal:

Trends in Cell Biology

Year:

1994

Language:

english

File:

PDF, 620 KB

english, 1994

19

NAADP receptors

Antony Galione, Margarida Ruas

Journal:

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

20

Dual effects of cyclic ADP-ribose on sarcoplasmic reticulum Ca2+ release and storage in cardiac myocytes isolated from guinea-pig and rat ventricle

Andrew T. Macgregor, Stevan Rakovic, Antony Galione, Derek A. Terrar

Journal:

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

21

Cell-permeant NAADP: A novel chemical tool enabling the study of Ca2+ signalling in intact cells

Raman Parkesh, Alexander M. Lewis, Parvinder K. Aley, Abdelilah Arredouani, Sara Rossi, Ricardo Tavares, Sridhar R. Vasudevan, Daniel Rosen, Antony Galione, James Dowden, Grant C. Churchill

Journal:

Year:

2008

Language:

english

File:

PDF, 709 KB

english, 2008

22

NAADP influences excitation–contraction coupling by releasing calcium from lysosomes in atrial myocytes

Thomas P. Collins, Rebecca Bayliss, Grant C. Churchill, Antony Galione, Derek A. Terrar

Journal:

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

23

Role of NAADP and cADPR in the Induction and Maintenance of Agonist-Evoked Ca2+ Spiking in Mouse Pancreatic Acinar Cells

Michiko Yamasaki, Justyn M. Thomas, Grant C. Churchill, Clive Garnham, Alexander M. Lewis, Jose-Manuel Cancela, Sandip Patel, Antony Galione

Journal:

Current Biology

Year:

2005

Language:

english

File:

PDF, 133 KB

english, 2005

24

Ca2+ Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites

Lianne C. Davis, Anthony J. Morgan, Margarida Ruas, Julian L. Wong, Richard M. Graeff, Albert J. Poustka, Hon Cheung Lee, Gary M. Wessel, John Parrington, Antony Galione

Journal:

Current Biology

Year:

2008

Language:

english

File:

PDF, 670 KB

english, 2008

25

TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP

Michael X. Zhu, Jianjie Ma, John Parrington, Antony Galione, A. Mark Evans

Journal:

Year:

2010

Language:

english

File:

PDF, 529 KB

english, 2010

26

Mechanisms of calcium release and sequestration in eggs of Chaetopterus pergamentaceus

Tracey Williams Thomas, William R. Eckberg, François Dubé, Antony Galione

Journal:

Year:

1998

Language:

english

File:

PDF, 957 KB

english, 1998

27

NAADP-induced calcium release in sea urchin eggs

Antony Galione, Sandip Patel, Grant C. Churchill

Journal:

Biology of the Cell

Year:

2000

Language:

english

File:

PDF, 875 KB

english, 2000

28

Two neuropeptides recruit different messenger pathways to evoke Ca2+ signals in the same cell

Denis Burdakov, Antony Galione

Journal:

Current Biology

Year:

2000

Language:

english

File:

PDF, 95 KB

english, 2000

29

A specific cyclic ADP-ribose antagonist inhibits cardiac excitation–contraction coupling

Stevan Rakovic, Antony Galione, Gloria A. Ashamu, Barry V.L. Potter, Derek A. Terrar

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 407 KB

english, 1996

30

Calmodulin Dissociation Mediates Desensitization of the cADPR-Induced Ca2+ Release Mechanism

Justyn M. Thomas, Robin J. Summerhill, Bradley R. Fruen, Grant C. Churchill, Antony Galione

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 90 KB

english, 2002

31

NAADP: A New Second Messenger for Glucose-Induced Ca2+ Responses in Clonal Pancreatic β Cells

Roser Masgrau, Grant C. Churchill, Anthony J. Morgan, Stephen J.H. Ashcroft, Antony Galione

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

32

Sperm Deliver a New Second Messenger: NAADP

Grant C. Churchill, John S. O'Neill, Roser Masgrau, Sandip Patel, Justyn M. Thomas, Armando A. Genazzani, Antony Galione

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

33

Nicotinic acid adenine dinucleotide phosphate triggers Ca2+ release from brain microsomes

Judit Bak, Peter White, György Timár, Ludwig Missiaen, Armando A. Genazzani, Antony Galione

Journal:

Current Biology

Year:

1999

Language:

english

File:

PDF, 128 KB

english, 1999

34

Coordination of Ca2+ signalling by NAADP

Sandip Patel, Grant C. Churchill, Antony Galione

Journal:

Trends in Biochemical Sciences

Year:

2001

Language:

english

File:

PDF, 848 KB

english, 2001

35

An N-Terminal Dileucine Motif Directs Two-Pore Channels to the Tonoplast of Plant Cells

Nina Larisch, Christina Schulze, Antony Galione, Petra Dietrich

Journal:

Year:

2012

Language:

english

File:

PDF, 81.73 MB

english, 2012

36

Inhibition of cADPR-Hydrolase by ADP-Ribose Potentiates cADPR Synthesis from β-NAD+

Armando A. Genazzani, Judith Bak, Antony Galione

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 79 KB

english, 1996

37

Ca2+ Release Induced by Cyclic ADP Ribose in Mice Lacking Type 3 Ryanodine Receptor

Rosella Fulceri, Rosetta Rossi, Roberto Bottinelli, Antonio Conti, Elena Intravaia, Antony Galione, Angelo Benedetti, Vincenzo Sorrentino, Carlo Reggiani

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 201 KB

english, 2001

38

Cyclic ADP-ribose-induced Ca2+ release from rat brain microsomes

Alison M. White, Stephen P. Watson, Antony Galione

Journal:

Year:

1993

Language:

english

File:

PDF, 362 KB

english, 1993

39

Human lymphocyte antigen CD38 catalyzes the production of cyclic ADP-ribose

Robin J. Summerhill, David G. Jackson, Antony Galione

Journal:

Year:

1993

Language:

english

File:

PDF, 325 KB

english, 1993

40

Nitric oxide induces intracellular Ca2+ mobilization and increases secretion of incorporated 5-hydroxytryptamine in rat pancreatic β-cells

Nicholas J. Willmott, Antony Galione, Paul A. Smith

Journal:

Year:

1995

Language:

english

File:

PDF, 550 KB

english, 1995

41

Cyclic aristeromycin diphosphate ribose: A potent and poorly hydrolysable Ca2+-mobilising mimic of cyclic adenosine diphosphate ribose

Victoria C. Bailey, Simon M. Fortt, Robin J. Summerhill, Antony Galione, Barry V.L. Potter

Journal:

Year:

1996

Language:

english

File:

PDF, 363 KB

english, 1996

42

Calcium store depletion potentiates a phosphodiesterase inhibitor- and dibutyryl cGMP-evoked calcium influx in rat pituitary GH3 cells

Nicholas J. Willmott, Judith Asselin, Antony Galione

Journal:

Year:

1996

Language:

english

File:

PDF, 371 KB

english, 1996

43

Investigating cADPR and NAADP in intact and broken cell preparations

Anthony J. Morgan, Antony Galione

Journal:

Year:

2008

Language:

english

File:

PDF, 745 KB

english, 2008

44

Phospholipase C-dependent Ca2+ release by worm and mammal sperm factors

Kethurah P Howell, Aurelia Skipwith, Antony Galione, William R Eckberg

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 117 KB

english, 2003

45

NAADP Mobilizes Ca2+ from Reserve Granules, Lysosome-Related Organelles, in Sea Urchin Eggs

Grant C. Churchill, Yuhei Okada, Justyn M. Thomas, Armando A. Genazzani, Sandip Patel, Antony Galione

Journal:

Year:

2002

Language:

english

File:

PDF, 313 KB

english, 2002

46

A Ca2+ release mechanism gated by the novel pyridine nucleotide, NAADP

Armando A. Genazzani, Antony Galione

Journal:

Trends in Pharmacological Sciences

Year:

1997

Language:

english

File:

PDF, 364 KB

english, 1997

47

Lithium-induced decrease in spontaneous Ca2+ oscillations in single GH3 rat pituitary cells

Mark A. Varney, Antony Galione, Steve P. Watson

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.40 MB

english, 1994

48

Ca2+-induced Ca2+ release and its modulation by cyclic ADP-ribose

Journal:

Trends in Pharmacological Sciences

Year:

1992

Language:

english

File:

PDF, 407 KB

english, 1992

49

Ip3 and the new wave in Ca2+ signalling: Inositol phosphates and calcium signalling. Advances in second messenger and phosphoprotein research, vol. 26 edited by James W. Putney, Jr, Raven Press, New York, 1992. £63.00 (xi + 404 pages) ISBN 0 88-167 883 X

Journal:

Trends in Pharmacological Sciences

Year:

1993

Language:

english

File:

PDF, 149 KB

english, 1993

50

Role of the Putative NAADP Receptor, Two-Pore Channel 2, in Ventricular Myocyte Responses to Isoproterenol

Elson, Laura C., Owen, William D., Gafson, Arie R., Parrington, John, Galione, Antony, Terrar, Derek A., Rakovic, Stevan

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010